Dietary Habit And Nutritional Status of Sickle Cell Patient In University of Benin Teaching Hospital (Ubth) Edo State Nigeria

Dietary Habit And Nutritional Status of Sickle Cell Patient In University of Benin Teaching Hospital (Ubth) Edo State Nigeria

Download Dietary Habit And Nutritional Status of Sickle Cell Patient In University of Benin Teaching Hospital (Ubth) Edo State Nigeria project materials: This project material is ready for students who are in need of it to aid their research.

ABSTRACT

Sickle cell disease (SCD) is a group of disorder that affect hemoglobin, the molecule in red blood cells that delivers oxygen to cell throughout the body.

People with this disorders have a typical hemoglobin molecule called hemoglobin S, which can distort red blood cells into sickle or crescent shape.

Characteristic features of this disorder include a low number of red blood cells (Anemia), repeated infections and periodic episodes of pain.

The aim of this study is to understand how the eating habit of people with SCD affect their nutritional status and how the micro nutrient contend in this food affect the severity and frequency of painful episode.

A sample of 171 patients were gotten from the university of Benin teaching hospital by simple random sampling and their anthropometric measurements  were taken, each was given a questionnaire and data was collected using this questionnaire.

According to data collected, it was noted that their dietary habit  on the consumption of meals like poultry, rice, beans and beef did not affect their BMI and frame size but affected the severity and frequency of painful episodes.

Those that always consume poultry, beans and rice experience lesser frequency and severity of pain than those that always consume beef.

The fact that red meat has the highest concentration of zinc(stallings,1999), which in high concentration causes anemia, impaired immune system(Anderson,1998), thereby causing high frequency and severity of pain. In conclusion patients with SCD should reduce their intake of beef(red meat).

INTRODUCTION

Sickle cell disease is a group disorders that affects heamoglobin, the molecule in red blood cells that delivers oxygen to cells throughout the body.

People with this disorder have typical hemoglobin molecule called heamoglobin S, which can distort red blood cells into a sickle or crescent shape.

Signs and symptoms of sickle cell disease usually begin in early childhood. Characteristic feature of this disorder includes a low number of red blood cell(anemia), repeated infection and periodic episode of pain.

The severity of the symptom varies from person to person, some people have mild symptoms while others are frequently hospitalized for more serious complications.

The signs and symptoms of sickle cell disease are caused by the sickling of red blood cells. When red bloods cell sickle, they break down prematurely which can lead to anemia.

Anemia can cause shortness of breath, fatigue, and the delayed growth and development in children. The rapid breakdown of red blood cells may also cause yellowing of the eyes and skin which are signs of jaundice.

Painful episode can occur when sickled red blood cells which are stiff and inflexible gets stuck in small blood vessels. These episode deprive tissues and organs of oxygen rich blood and can lead to organ damage, especially in the lungs, kidneys, spleen and brain.

A particularly serious complication of sickle cell disease is high blood pressure in the blood vessels that supplies the lungs (pulmonary hypertension), pulmonary hypertension occurs in about 1/3 of adult with sickle cell disease and can lead to heart failure.

REFERENCE

Brown K, Subrammy C, May W, et al. Hepatic iron overload in children with sickle cell anemia on chronic transfusion therapy (2005).pg 124-133

Dris A, Kwaku A, Hibbert J, Adambowice T, Stiles JK, Sickle cell disease in the post gnomic era. 2009: 2:23 – 48.

Hegman MB, Katz R, Hurst D, et al. Growth retardation in sickle cell disease treated by Nutritional support 2005: Pg 75 ch 3.

Hibbert JM, Creary MS, Gee BE et al. Erythropoiesis and Myocardial energy requirements contribute to the hypermetabolism of childhood sickle cell anemia. pediatricGastroenterol and Nutr. 2006; 43(5): 650.7.

Hoffer LJ, carmel R et al. (2003) supplementation in sickle cell anemia.1st edition ch 4

Hyacinth HI, Gee BE, Hibbert JM (2010) the role of nutrition in sickle cell disease.Nutrition metabolic Insights 3rd edition Ch 3 PP 57 – 67.

Kumar V, Abbas AK, Fausto N. Robins and cotran Pathologic basis of disease of organs systems Red blood cells. And bleeding disorder – sickle cell disease pp (28 – 32) Chpt 13.

Makani, J, Cox SE, soka D (2014) mortality in sickle cell anemia in Africa ,1st edition PP 57 & 58.

Malik P (2009) Nutrition and heamatopoiesis 6th edition Ch 5 page 152 – 160.

Mehta AB, Hoffbrand AV. Heamatology at a glance. 3rdeditim 2013 Glowel public Library 2 Hemolytic  anemias Vs indented defects of heamoglobin – sickle cell disease Pp 50 Ch 17.

Mohanty D, Mukherjee MB. (2008) Iron deficiency Anemia in Sickle cell disorders in india.

O’Dell BL (2010) Role of Zinc in Plasma Membrane Function. 3rd edition  Pp 67-75

Ohinishi ST, Ohinishi T (2011). In Vitro effects of aged garlic extract and other nutritional supplements on sickle cell erythrocytes. 1st edition Ch 7

Ohnishi S T, Ohnishi T, OgunmolaGB(2010). Sickle cell anemia: a potential nutritional approach for a molecular disease Pg 104 Ch 5.

Okeahialam TC (2003) Iron deficiency is sickle cell anemia in Nigerian Children. Pp 187

Prasad AJ (2003) Clinical spectrum of human Zinc deficiency.Pp 34

Be the first to comment

Leave a Reply

Your email address will not be published.


*