An Overview of Step Pedcare Is Presented
Current literature suggests that griseofulvin continues to be effective in most patients with Tinea capitis. Ketoconazole is no more effective than griseofulvin and causes more adverse events and drug interactions. Adamson (2001)
DRUG STEPS OVERVIEW
Safety and tolerability |
Mild adverse effects are Associated with grisesofulvin, Ketoconazole, terbinafine and itraconazole. While ketoconazole as associated with adrenal insufficiency, myopathy and urticaria in adults with treat Tinea capitis, none of these adverse events were noted in the pediatric studies. Although clinically significant drug interactions are common with Ketoconazole and itraconazole, their prevalence was not apparent in the pediatric studies. |
Effectiveness |
Griseofulvin continues to be effective as a first –line drug in many patients. Terbinafine and traconazole may be used in unresponsive causes. Terbinafine and traconazole are effective in pulse and traditional does. However strong comparative clinical trial data supporting their use are scarce. |
Price |
Griseofulvin is the most costly agent supported POEMs (patient- oriented evidence that matters e.g, compliance rates and clinical cure, such as hair growth, decreased inflammation, and relapse rated for treating Tinea capitis. Other antifungal agents are less costly, however, strong clinical data are lacking to support their use. |
REFERENCES
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Al- Doory, Y.J, Kalter, S.S. (1967). The isolation of histoplasma disboisi and keratindphilic fungi from soils of East Africa.
Anosike J.C, Keke I.R, Uweazuoke J.C, Anozie J.C, Obiukwu C.E, Nwoke B.E.B, Amaijuoyi O.U. (2005). Prevalence and distribution of ringworm infection in primary school children in parts of Eastern, Nigeria. Journal of Appl. Sc. And Environ. Management.9 (3):21-25
Ayadi A, Borgi N, Makni F.(1993).Prevalence of Superficial mycoses in an urban ecosystem in sfax (Tunisia).Bull.Soc. pathol. Exotique. 86:188-9.
Baron E.J, Murray P.R., jorgensen J.H, pfaller M.A, Yalken R.H (2003) manual of clinical microbiology. (8th ed.) sm press, Washington. 1798 –1817 pp.
Egere, T. U, Gugnani, H.G. (1980). Etiology of dermatopphytosis in Eastern Nigeria. Mykosen, 23, 178-18.
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