– Studies of Renal and Hepatic Parameters in Children with Acute Malaria Parasitaemia Attending Federal Medical Centre Owerri, Imo State –
Download Studies of Renal and Hepatic Parameters in Children with Acute Malaria Parasitaemia Attending Federal Medical Centre Owerri, Imo State. project materials: This project material is ready for students who are in need of it to aid their research.
INTRODUCTION
Malaria is a significant public health problem in more than 100 countries of the world and causes an estimated 200 million new infections every year.
Despite the significant effort to educate this dangerous disease, lack of complete knowledge of its pathophysiology hampers the success in this enterprise. It is wide spread in tropical and sub tropical regions, including part of America, Asia and Africa.
Each year, there are approximately 350-500 million cases of malaria (WHO, 2008) Killing between one and three million people, the majority of whom are young children in sub- Sahara Africa . (Snow et al., 2005). 90% of malaria-related deaths occur in sub-Saharan Africa (Green Wood et al., 2005).
Annually, some 300 million people get ill from malaria, about one million victims die every year, many of them children.
In Africa, one child die of malaria about every 30 seconds according to the world health organization (WHO) “science still has no magic bullet for malaria and many doubt that such a solution will never exist”.
Malaria as well as being one of the most prevalent and dangerous disease known to man, is also by far the world’s most important tropical disease (Trigg and Kondrachi, 1993).
The prevalence of malaria has been escalating at an alarming rate in the last decade. As a matter of fact, the prevalence of malaria in Owerri areas of Imo State (Ukpai and Akoju, 2001) reveals that Owerri has a high rate of malaria infections of 75% and the infection with plasmodiuTn falciparum ranks the highest. Hence, malaria is a major cause of morbidity and mortality.
REFERENCES
Akanbi, O.M., Omonkhua, A.A and Cyril-Olutayo, M.C.(2014). Effect of methanolic extract of stem bark of Anogeissusleiocarpus on liver function of mice infected with Plasmodium berghei. Journal of Herbs Spices Medicinal Plants. 20(3):350-358.
Anyasor, G.N and Olorunsogo, O.O.(2011). Evaluation of selected biochemical parameters in renal and hepatic functions following oral administration of artesunate to albino rats. Researcher 3(7):45-50
Burtis, E and Ashwood, B. (2001). Liver functions. Tietz Fundamentals of Clinical Chemistry, 5th (ed.), Saunders Company, Philadelphia pp. 748-770.
Cheesbrough, M.(1991). Medical Laboratory Manual for’ Clinical Chemistry. Snaap Press, Enugu, Nigeria p 27.
Christen, P and Metzier, D.E.(1985). Aminotransferases. Wiley Interscience Inc., New York pp. 49-60.
Di Giorgio, J., Henry, R. J., Cannon. D. C and Winkelman, J.W. (1974). Non-protein Nitrogenous constituents. Clinical Chemistry Principles and Technics. 2nd edition. Hagerstown, Harper and Row pp. 511 -522.
Dzeing-Ella, A., Pascal, C., Nze, O., Rose, T., Timothy, P.. Ebele, J.l., Emeka, E.N., Nnenna, C.A., Ignatius, C.M and Ebele. A.(2010). Severe Falciparum malaria in Gabonese children: clinical and laboratory features. Journal of Malaria. 4(5):23-30.
Ebele, J.l., Emeka, E.N., Nnenna, C.A., Ignatius, C.M and Ebele.A.(2010). Malaria parasitaemia: effect on serum sodium and potassium levels. International Journal of Tropical Medicine. 5(3):46-49.
Be the first to comment