Evaluate The Effects Of Age On Some Sex Steroids, And Markers Of Oxidative Stress In Some Infertile Male Subjects In Owerri Metropolis
INTRODUCTION
Infertility is the inability of a person, animal, or plant to reproduce by natural means. It is usually not the natural state of a healthy adults organism, expect notably among certain eusocial species (mostly haplodiploid insects). (Dunson et al., 2012).
Male infertility refers to a male’s inability to cause pregnancy in a fertile female. In humans, it affects approximately 7% of all men (Brugh and Lipshultz, 2014).
Male infertility is commonly due to deficiencies in the semen and semen quality is used as a surrogate measure of male fecundity. (Lotti and Maggi, 2014)
Age is a time of life usually defined in years or how long something has existed. (word wed dictionary, 2014). Some research suggests that increased male age is associated with a decline in semen volume, sperm motility and sperm morphology.
In studies that controlled for female age, comparisons between men under 30 and men over 50 found relative decreases in pregnancy rates between 23% and 38% .(Kidd et al., 2012).
It suggests that sperm count declines with age, with men aged 50-80 years producing sperm at an average rate of 75% compared with men aged 20-50 years.
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